Thrombolytic therapy for prosthetic cardiac valve thrombosis

[Thrombolytic therapy in prosthetic valve thrombosis].

Successful Use of Two Thrombolytic Drugs in Prosthetic Mitral and Aortic Valve Thrombosis

Introduction: Prosthetic valve thrombosis is a rare and severe complication of valve replacement, most often encountered with a mechanical prosthesis. The significant morbidity and mortality associated with this condition warrant rapid diagnostic evaluation. Although surgery is the first-line therapy in symptomatic obstructive mechanical valve thrombosis, thrombolytic therapy has been used as a...

Therapy and Prevention Prosthetic Valve Thrombosis

In a prospective, randomized, parallel study, two regimens of platelet-suppressant therapy (PST) dipyridamole-aspirin and pentoxifylline-aspirin were compared with standard oral anticoagulation with warfarin in the prevention of prosthetic heart valve thromboembolism. In the entire group of 254 patients followed for 395.6 patient-years, the thromboembolic rate was significantly less in the warf...

Management of Patients With Prosthetic Valve Thrombosis After Failed Thrombolytic Therapy.

relate their observation that Holter abnormalities typically precede structural findings on imaging. In our clinical practice, and borne out by the data from our study, pediatric patients rarely fulfill the major criterion for arrhythmias. Arrhythmias as a minor criterion were more prevalent but did not distinguish between the different diagnostic certainty groups. Dr. te Riele and colleagues h...

Management of prosthetic valve thrombosis

Valvular re-replacement is the traditional therapy for prosthetic valve thrombosis[1–7]. Systemic fibrinolysis, leaving the valve substitute in place, and thrombectomy have been suggested as alternative therapeutic options. In order to weigh the risks against the benefits of surgical versus thrombolytic treatment, we performed a metaanalysis of data from 23 major studies reported since 1980 in ...